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Current Species: Onchocerca flexuosa (compared to KEGG Release 46)
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| | Current cutoff: 1e-05 |
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1.1 Carbohydrate Metabolism
Glycolysis / GluconeogenesisEC 2.7.1.40 ATP:pyruvate 2-O-phosphotransferase NemaPath viewer EC 5.3.1.9 D-glucose-6-phosphate aldose-ketose-isomerase NemaPath viewer EC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 5.1.3.15 D-glucose-6-phosphate 1-epimerase NemaPath viewer EC 2.7.1.69 protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase NemaPath viewer EC 4.1.1.1 2-oxo-acid carboxy-lyase (aldehyde-forming) NemaPath viewer EC 2.3.1.12 acetyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-acetyltransferase NemaPath viewer
Citrate cycle (TCA cycle)EC 4.1.1.32 GTP:oxaloacetate carboxy-lyase (adding GTP; NemaPath viewer EC 4.2.1.2 (S)-malate hydro-lyase (fumarate-forming) NemaPath viewer EC 1.1.1.42 isocitrate:NADP+ oxidoreductase (decarboxylating) NemaPath viewer EC 6.2.1.4 succinate:CoA ligase (GDP-forming) NemaPath viewer EC 1.1.1.41 isocitrate:NAD+ oxidoreductase (decarboxylating) NemaPath viewer
Pentose phosphate pathwayEC 2.7.6.1 ATP:D-ribose-5-phosphate diphosphotransferase NemaPath viewer EC 5.3.1.9 D-glucose-6-phosphate aldose-ketose-isomerase NemaPath viewer
Inositol metabolismEC 1.-.-.- NO DESCRIPTION NemaPath viewer
Pentose and glucuronate interconversionsEC 1.1.1.56 ribitol:NAD+ 2-oxidoreductase NemaPath viewer
Fructose and mannose metabolismEC 2.7.1.69 protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase NemaPath viewer EC 3.1.3.- NO DESCRIPTION NemaPath viewer EC 2.4.1.- NO DESCRIPTION NemaPath viewer EC 1.1.1.271 GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing) NemaPath viewer EC 1.1.1.- NO DESCRIPTION NemaPath viewer
Galactose metabolismEC 5.1.3.2 UDP-glucose 4-epimerase NemaPath viewer EC 2.7.1.6 ATP:D-galactose 1-phosphotransferase NemaPath viewer EC 1.1.1.- NO DESCRIPTION NemaPath viewer EC 2.7.1.69 protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase NemaPath viewer
Ascorbate and aldarate metabolismEC 1.14.-.- NO DESCRIPTION NemaPath viewer EC 2.7.1.69 protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase NemaPath viewer EC 4.1.1.- NO DESCRIPTION NemaPath viewer EC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 3.1.1.- NO DESCRIPTION NemaPath viewer EC 3.1.3.- NO DESCRIPTION NemaPath viewer EC 3.7.1.- NO DESCRIPTION NemaPath viewer EC 1.1.1.- NO DESCRIPTION NemaPath viewer EC 5.1.3.- NO DESCRIPTION NemaPath viewer
Starch and sucrose metabolismEC 2.7.1.69 protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase NemaPath viewer EC 3.2.1.28 alpha,alpha-trehalose glucohydrolase NemaPath viewer EC 5.3.1.9 D-glucose-6-phosphate aldose-ketose-isomerase NemaPath viewer EC 3.6.1.- NO DESCRIPTION NemaPath viewer
Nucleotide sugars metabolismEC 4.2.1.46 dTDP-glucose 4,6-hydro-lyase NemaPath viewer EC 1.1.1.- NO DESCRIPTION NemaPath viewer EC 5.1.3.2 UDP-glucose 4-epimerase NemaPath viewer
Aminosugars metabolismEC 1.1.1.- NO DESCRIPTION NemaPath viewer EC 3.5.1.41 chitin amidohydrolase NemaPath viewer EC 3.1.3.- NO DESCRIPTION NemaPath viewer EC 2.7.1.69 protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase NemaPath viewer EC 3.1.4.- NO DESCRIPTION NemaPath viewer
Inositol phosphate metabolismEC 3.1.3.56 1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase NemaPath viewer EC 3.1.4.11 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate NemaPath viewer EC 2.7.1.137 ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase NemaPath viewer EC 2.7.1.- NO DESCRIPTION NemaPath viewer EC 2.7.1.68 ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase NemaPath viewer
Pyruvate metabolismEC 4.1.1.32 GTP:oxaloacetate carboxy-lyase (adding GTP; NemaPath viewer EC 2.7.1.40 ATP:pyruvate 2-O-phosphotransferase NemaPath viewer EC 1.1.1.40 (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating) NemaPath viewer EC 2.3.1.9 acetyl-CoA:acetyl-CoA C-acetyltransferase NemaPath viewer EC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 6.4.1.2 acetyl-CoA:carbon-dioxide ligase (ADP-forming) NemaPath viewer EC 1.1.1.39 (S)-malate:NAD+ oxidoreductase (decarboxylating) NemaPath viewer EC 4.1.1.- NO DESCRIPTION NemaPath viewer EC 1.2.3.3 pyruvate:oxygen 2-oxidoreductase (phosphorylating) NemaPath viewer EC 3.1.2.6 S-(2-hydroxyacyl)glutathione hydrolase NemaPath viewer EC 1.2.2.2 pyruvate:ferricytochrome-b1 oxidoreductase NemaPath viewer EC 2.3.1.12 acetyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-acetyltransferase NemaPath viewer EC 1.1.1.38 (S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating) NemaPath viewer EC 1.1.2.3 (S)-lactate:ferricytochrome-c 2-oxidoreductase NemaPath viewer
Glyoxylate and dicarboxylate metabolismEC 4.1.1.47 glyoxylate carboxy-lyase (dimerizing; NemaPath viewer EC 4.1.1.8 oxalyl-CoA carboxy-lyase (formyl-CoA-forming) NemaPath viewer
Propanoate metabolismEC 6.2.1.4 succinate:CoA ligase (GDP-forming) NemaPath viewer EC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 1.3.99.3 acyl-CoA:acceptor 2,3-oxidoreductase NemaPath viewer EC 6.4.1.2 acetyl-CoA:carbon-dioxide ligase (ADP-forming) NemaPath viewer EC 2.3.1.9 acetyl-CoA:acetyl-CoA C-acetyltransferase NemaPath viewer
Butanoate metabolismEC 2.3.1.9 acetyl-CoA:acetyl-CoA C-acetyltransferase NemaPath viewer EC 2.2.1.6 pyruvate:pyruvate acetaldehydetransferase (decarboxylating) NemaPath viewer EC 3.1.1.- NO DESCRIPTION NemaPath viewer EC 1.1.1.- NO DESCRIPTION NemaPath viewer EC 1.3.99.2 butanoyl-CoA:acceptor 2,3-oxidoreductase NemaPath viewer EC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 1.1.1.35 (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase NemaPath viewer EC 1.1.1.30 (R)-3-hydroxybutanoate:NAD+ oxidoreductase NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer
C5-Branched dibasic acid metabolismEC 2.2.1.6 pyruvate:pyruvate acetaldehydetransferase (decarboxylating) NemaPath viewer
Overview of biosynthetic pathways |
1.2 Energy Metabolism
Oxidative phosphorylationEC 1.9.3.- NemaPath viewer EC 3.6.3.14 ATP phosphohydrolase (H+-transporting) NemaPath viewer EC 1.6.5.3 NADH:ubiquinone oxidoreductase NemaPath viewer EC 1.6.99.5 NADH:(quinone-acceptor) oxidoreductase NemaPath viewer EC 1.9.3.1 ferrocytochrome-c:oxygen oxidoreductase NemaPath viewer EC 3.6.3.10 ATP phosphohydrolase (H+/K+-exchanging) NemaPath viewer EC 3.6.3.6 ATP phosphohydrolase (H+-exporting) NemaPath viewer EC 1.10.3.- NemaPath viewer EC 1.10.2.2 ubiquinol:ferricytochrome-c oxidoreductase NemaPath viewer
PhotosynthesisEC 3.6.3.14 ATP phosphohydrolase (H+-transporting) NemaPath viewer
Photosynthesis - antenna proteinsEC 4.-.-.- NemaPath viewer
Methane metabolismEC 1.11.1.7 donor:hydrogen-peroxide oxidoreductase NemaPath viewer EC 1.14.13.- NO DESCRIPTION NemaPath viewer
Carbon fixationEC 1.1.1.39 (S)-malate:NAD+ oxidoreductase (decarboxylating) NemaPath viewer EC 1.1.1.40 (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating) NemaPath viewer EC 2.7.1.40 ATP:pyruvate 2-O-phosphotransferase NemaPath viewer
Reductive carboxylate cycle (CO2 fixation)EC 4.2.1.2 (S)-malate hydro-lyase (fumarate-forming) NemaPath viewer EC 1.1.1.42 isocitrate:NADP+ oxidoreductase (decarboxylating) NemaPath viewer
Nitrogen metabolism
Sulfur metabolismEC 2.7.1.25 ATP:adenylyl-sulfate 3'-phosphotransferase NemaPath viewer EC 2.7.7.4 ATP:sulfate adenylyltransferase NemaPath viewer |
1.3 Lipid Metabolism
Fatty acid biosynthesisEC 6.4.1.2 acetyl-CoA:carbon-dioxide ligase (ADP-forming) NemaPath viewer EC 1.1.1.100 (3R)-3-hydroxyacyl-[acyl-carrier protein]:NADP+ oxidoreductase NemaPath viewer
Fatty acid elongation in mitochondriaEC 1.1.1.35 (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase NemaPath viewer EC 2.3.1.16 acyl-CoA:acetyl-CoA C-acyltransferase NemaPath viewer
Fatty acid metabolismEC 2.3.1.16 acyl-CoA:acetyl-CoA C-acyltransferase NemaPath viewer EC 1.3.99.2 butanoyl-CoA:acceptor 2,3-oxidoreductase NemaPath viewer EC 1.3.99.- NO DESCRIPTION NemaPath viewer EC 2.3.1.9 acetyl-CoA:acetyl-CoA C-acetyltransferase NemaPath viewer EC 1.1.1.35 (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase NemaPath viewer EC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 1.3.99.3 acyl-CoA:acceptor 2,3-oxidoreductase NemaPath viewer EC 6.2.1.3 acid:CoA ligase (AMP-forming) NemaPath viewer
Synthesis and degradation of ketone bodiesEC 2.3.1.9 acetyl-CoA:acetyl-CoA C-acetyltransferase NemaPath viewer EC 1.1.1.30 (R)-3-hydroxybutanoate:NAD+ oxidoreductase NemaPath viewer
Biosynthesis of steroidsEC 1.3.1.21 cholesterol:NADP+ Delta7-oxidoreductase NemaPath viewer EC 5.4.99.7 (S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming) NemaPath viewer EC 1.3.1.70 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ NemaPath viewer EC 1.1.1.34 (R)-mevalonate:NADP+ oxidoreductase (CoA-acylating) NemaPath viewer EC 1.17.1.2 isopentenyl-diphosphate:NAD(P)+ oxidoreductase NemaPath viewer
Bile acid biosynthesisEC 2.3.1.16 acyl-CoA:acetyl-CoA C-acyltransferase NemaPath viewer EC 1.3.99.- NO DESCRIPTION NemaPath viewer EC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 1.1.1.- NO DESCRIPTION NemaPath viewer EC 3.1.1.13 steryl-ester acylhydrolase NemaPath viewer
C21-Steroid hormone metabolismEC 1.1.1.146 11beta-hydroxysteroid:NADP+ 11-oxidoreductase NemaPath viewer
Androgen and estrogen metabolismEC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 1.1.1.62 estradiol-17beta:NAD(P)+ 17-oxidoreductase NemaPath viewer EC 1.1.1.146 11beta-hydroxysteroid:NADP+ 11-oxidoreductase NemaPath viewer EC 2.1.1.- NO DESCRIPTION NemaPath viewer EC 3.1.6.1 aryl-sulfate sulfohydrolase NemaPath viewer
Glycerolipid metabolismEC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 3.1.1.3 triacylglycerol acylhydrolase NemaPath viewer EC 2.7.1.- NO DESCRIPTION NemaPath viewer EC 2.4.1.- NO DESCRIPTION NemaPath viewer EC 2.3.1.51 acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase NemaPath viewer
Glycerophospholipid metabolismEC 3.1.1.7 acetylcholine acetylhydrolase NemaPath viewer EC 2.7.1.32 ATP:choline phosphotransferase NemaPath viewer EC 2.3.1.43 phosphatidylcholine:sterol O-acyltransferase NemaPath viewer EC 3.1.1.4 phosphatidylcholine 2-acylhydrolase NemaPath viewer EC 2.7.8.2 CDP-choline:1,2-diacyl-sn-glycerol cholinephosphotransferase NemaPath viewer EC 2.7.1.82 ATP:ethanolamine O-phosphotransferase NemaPath viewer EC 2.7.8.8 CDP-diacylglycerol:L-serine 3-sn-phosphatidyltransferase NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 1.1.1.101 1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase NemaPath viewer EC 2.3.1.51 acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase NemaPath viewer
Ether lipid metabolismEC 2.7.8.2 CDP-choline:1,2-diacyl-sn-glycerol cholinephosphotransferase NemaPath viewer EC 3.1.4.- NO DESCRIPTION NemaPath viewer EC 2.3.1.51 acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase NemaPath viewer EC 3.1.3.- NO DESCRIPTION NemaPath viewer EC 3.1.1.4 phosphatidylcholine 2-acylhydrolase NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 1.1.1.101 1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase NemaPath viewer EC 3.1.1.47 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase NemaPath viewer
Arachidonic acid metabolismEC 3.1.1.4 phosphatidylcholine 2-acylhydrolase NemaPath viewer EC 3.3.2.10 epoxide hydrolase NemaPath viewer
Linoleic acid metabolismEC 3.1.1.4 phosphatidylcholine 2-acylhydrolase NemaPath viewer EC 1.1.1.- NO DESCRIPTION NemaPath viewer
alpha-Linolenic acid metabolismEC 1.-.-.- NO DESCRIPTION NemaPath viewer EC 2.3.1.16 acyl-CoA:acetyl-CoA C-acyltransferase NemaPath viewer EC 3.1.1.4 phosphatidylcholine 2-acylhydrolase NemaPath viewer EC 3.1.2.- NO DESCRIPTION NemaPath viewer
Sphingolipid metabolismEC 2.4.1.- NO DESCRIPTION NemaPath viewer EC 2.3.1.50 palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) NemaPath viewer EC 3.1.3.- NO DESCRIPTION NemaPath viewer EC 1.14.-.- NO DESCRIPTION NemaPath viewer EC 1.1.1.102 D-erythro-dihydrosphingosine:NADP+ 3-oxidoreductase NemaPath viewer EC 3.1.6.1 aryl-sulfate sulfohydrolase NemaPath viewer |
1.4 Nucleotide Metabolism
Purine metabolismEC 4.6.1.2 GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) NemaPath viewer EC 3.6.4.1 ATP phosphohydrolase (actin-translocating) NemaPath viewer EC 3.1.5.1 dGTP triphosphohydrolase NemaPath viewer EC 4.1.1.- NO DESCRIPTION NemaPath viewer EC 3.5.2.- NO DESCRIPTION NemaPath viewer EC 2.7.1.25 ATP:adenylyl-sulfate 3'-phosphotransferase NemaPath viewer EC 2.7.7.6 nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) NemaPath viewer EC 2.7.7.8 polyribonucleotide:phosphate nucleotidyltransferase NemaPath viewer EC 2.7.7.4 ATP:sulfate adenylyltransferase NemaPath viewer EC 2.7.4.3 ATP:AMP phosphotransferase NemaPath viewer EC 2.4.2.22 XMP:diphosphate 5-phospho-alpha-D-ribosyltransferase NemaPath viewer EC 2.7.6.1 ATP:D-ribose-5-phosphate diphosphotransferase NemaPath viewer EC 2.4.2.8 IMP:diphosphate phospho-D-ribosyltransferase NemaPath viewer EC 3.6.1.3 ATP phosphohydrolase NemaPath viewer EC 2.7.1.40 ATP:pyruvate 2-O-phosphotransferase NemaPath viewer EC 2.7.4.8 ATP:(d)GMP phosphotransferase NemaPath viewer EC 3.6.1.15 unspecific diphosphate phosphohydrolase NemaPath viewer EC 2.7.7.- NemaPath viewer EC 2.7.4.6 ATP:nucleoside-diphosphate phosphotransferase NemaPath viewer EC 2.4.2.7 AMP:diphosphate phospho-D-ribosyltransferase NemaPath viewer
Pyrimidine metabolismEC 2.7.4.10 nucleoside-triphosphate:AMP phosphotransferase NemaPath viewer EC 2.7.7.- NemaPath viewer EC 2.7.7.8 polyribonucleotide:phosphate nucleotidyltransferase NemaPath viewer EC 4.2.1.70 uracil hydro-lyase (adding D-ribose 5-phosphate; NemaPath viewer EC 2.4.2.10 orotidine-5'-phosphate:diphosphate NemaPath viewer EC 6.3.4.2 UTP:ammonia ligase (ADP-forming) NemaPath viewer EC 2.7.7.6 nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) NemaPath viewer EC 2.7.4.6 ATP:nucleoside-diphosphate phosphotransferase NemaPath viewer EC 2.7.4.14 ATP:CMP phosphotransferase NemaPath viewer |
1.5 Amino Acid Metabolism
Urea cycle and metabolism of amino groupsEC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 4.1.1.- NO DESCRIPTION NemaPath viewer
Glutamate metabolismEC 1.5.1.12 (S)-1-pyrroline-5-carboxylate:NAD+ oxidoreductase NemaPath viewer EC 6.1.1.17 L-glutamate:tRNAGlu ligase (AMP-forming) NemaPath viewer EC 6.3.2.2 L-glutamate:L-cysteine gamma-ligase (ADP-forming) NemaPath viewer
Alanine and aspartate metabolismEC 2.3.1.12 acetyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-acetyltransferase NemaPath viewer EC 6.1.1.7 L-alanine:tRNAAla ligase (AMP-forming) NemaPath viewer
Glycine, serine and threonine metabolismEC 1.2.1.11 L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating) NemaPath viewer EC 2.3.1.29 acetyl-CoA:glycine C-acetyltransferase NemaPath viewer EC 4.1.2.5 L-threonine acetaldehyde-lyase (glycine-forming) NemaPath viewer EC 2.7.8.8 CDP-diacylglycerol:L-serine 3-sn-phosphatidyltransferase NemaPath viewer EC 2.7.1.32 ATP:choline phosphotransferase NemaPath viewer EC 2.3.1.37 succinyl-CoA:glycine C-succinyltransferase (decarboxylating) NemaPath viewer EC 1.1.1.- NO DESCRIPTION NemaPath viewer EC 3.1.3.3 O-phosphoserine phosphohydrolase NemaPath viewer
Methionine metabolism
Cysteine metabolismEC 6.1.1.16 L-cysteine:tRNACys ligase (AMP-forming) NemaPath viewer
Valine, leucine and isoleucine degradationEC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 1.3.99.3 acyl-CoA:acceptor 2,3-oxidoreductase NemaPath viewer EC 2.3.1.16 acyl-CoA:acetyl-CoA C-acyltransferase NemaPath viewer EC 1.3.99.10 3-methylbutanoyl-CoA:acceptor oxidoreductase NemaPath viewer EC 1.3.99.2 butanoyl-CoA:acceptor 2,3-oxidoreductase NemaPath viewer EC 2.3.1.9 acetyl-CoA:acetyl-CoA C-acetyltransferase NemaPath viewer EC 1.1.1.35 (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase NemaPath viewer
Valine, leucine and isoleucine biosynthesisEC 1.1.1.85 (2R,3S)-3-isopropylmalate:NAD+ oxidoreductase NemaPath viewer EC 2.2.1.6 pyruvate:pyruvate acetaldehydetransferase (decarboxylating) NemaPath viewer EC 6.1.1.5 L-isoleucine:tRNAIle ligase (AMP-forming) NemaPath viewer
Lysine biosynthesisEC 1.2.1.11 L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating) NemaPath viewer EC 2.6.1.17 N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate NemaPath viewer EC 6.1.1.6 L-lysine:tRNALys ligase (AMP-forming) NemaPath viewer
Lysine degradationEC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 1.14.11.4 L-lysine-[procollagen],2-oxoglutarate:oxygen oxidoreductase NemaPath viewer EC 3.4.-.- NO DESCRIPTION NemaPath viewer EC 2.1.1.43 S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase NemaPath viewer EC 1.1.1.- NO DESCRIPTION NemaPath viewer EC 2.3.1.9 acetyl-CoA:acetyl-CoA C-acetyltransferase NemaPath viewer EC 1.1.1.35 (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase NemaPath viewer
Arginine and proline metabolismEC 3.4.11.5 NO DESCRIPTION NemaPath viewer EC 1.5.1.12 (S)-1-pyrroline-5-carboxylate:NAD+ oxidoreductase NemaPath viewer EC 6.1.1.15 L-proline:tRNAPro ligase (AMP-forming) NemaPath viewer
Histidine metabolismEC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 4.1.1.28 aromatic-L-amino-acid carboxy-lyase NemaPath viewer EC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 2.4.2.17 1-(5-phospho-D-ribosyl)-ATP:diphosphate NemaPath viewer EC 2.4.2.- NO DESCRIPTION NemaPath viewer EC 4.1.1.22 L-histidine carboxy-lyase (histamine-forming) NemaPath viewer EC 3.5.2.- NO DESCRIPTION NemaPath viewer EC 2.1.1.- NO DESCRIPTION NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer
Tyrosine metabolismEC 4.1.1.25 L-tyrosine carboxy-lyase (tyramine-forming) NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 4.1.1.- NO DESCRIPTION NemaPath viewer EC 4.1.1.28 aromatic-L-amino-acid carboxy-lyase NemaPath viewer EC 1.14.17.1 3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase NemaPath viewer EC 2.1.1.- NO DESCRIPTION NemaPath viewer EC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 1.14.18.1 monophenol,L-dopa:oxygen oxidoreductase NemaPath viewer
Phenylalanine metabolismEC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 3.7.1.- NO DESCRIPTION NemaPath viewer EC 1.11.1.7 donor:hydrogen-peroxide oxidoreductase NemaPath viewer EC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 4.1.1.28 aromatic-L-amino-acid carboxy-lyase NemaPath viewer
Tryptophan metabolismEC 4.1.1.- NO DESCRIPTION NemaPath viewer EC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 4.1.1.74 3-(indol-3-yl)pyruvate carboxy-lyase NemaPath viewer EC 4.1.1.28 aromatic-L-amino-acid carboxy-lyase NemaPath viewer EC 2.3.1.9 acetyl-CoA:acetyl-CoA C-acetyltransferase NemaPath viewer EC 1.1.1.35 (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase NemaPath viewer EC 2.1.1.- NO DESCRIPTION NemaPath viewer
Phenylalanine, tyrosine and tryptophan biosynthesis |
1.6 Metabolism of Other Amino Acids
beta-Alanine metabolismEC 1.3.99.3 acyl-CoA:acceptor 2,3-oxidoreductase NemaPath viewer EC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer
Taurine and hypotaurine metabolismEC 2.3.3.15 acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate NemaPath viewer
Aminophosphonate metabolismEC 2.7.8.2 CDP-choline:1,2-diacyl-sn-glycerol cholinephosphotransferase NemaPath viewer EC 2.1.1.- NO DESCRIPTION NemaPath viewer
Selenoamino acid metabolismEC 2.7.1.25 ATP:adenylyl-sulfate 3'-phosphotransferase NemaPath viewer EC 2.7.7.4 ATP:sulfate adenylyltransferase NemaPath viewer EC 2.1.1.- NO DESCRIPTION NemaPath viewer
Cyanoamino acid metabolism
D-Glutamine and D-glutamate metabolism
D-Arginine and D-ornithine metabolism
D-Alanine metabolism
Glutathione metabolismEC 6.3.2.2 L-glutamate:L-cysteine gamma-ligase (ADP-forming) NemaPath viewer EC 1.1.1.42 isocitrate:NADP+ oxidoreductase (decarboxylating) NemaPath viewer |
1.7 Glycan Biosynthesis and Metabolism
N-Glycan biosynthesisEC 2.4.1.145 UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha NemaPath viewer EC 2.4.1.- NO DESCRIPTION NemaPath viewer EC 3.2.1.106 mannosyl-oligosaccharide glucohydrolase NemaPath viewer EC 2.4.1.119 dolichyl-diphosphooligosaccharide:protein-L-asparagine NemaPath viewer
N-Glycan degradationEC 3.5.1.26 N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase NemaPath viewer
O-Glycan biosynthesisEC 2.4.1.41 UDP-N-acetyl-D-galactosamine:polypeptide NemaPath viewer EC 2.4.1.- NO DESCRIPTION NemaPath viewer
High-mannose type N-glycan biosynthesisEC 2.7.-.- NO DESCRIPTION NemaPath viewer EC 2.4.1.- NO DESCRIPTION NemaPath viewer
Glycosaminoglycan degradation
Chondroitin sulfate biosynthesis
Keratan sulfate biosynthesisEC 2.4.1.- NO DESCRIPTION NemaPath viewer
Heparan sulfate biosynthesis
Lipopolysaccharide biosynthesisEC 2.7.-.- NO DESCRIPTION NemaPath viewer EC 2.-.-.- NO DESCRIPTION NemaPath viewer EC 3.1.1.- NO DESCRIPTION NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 2.4.1.- NO DESCRIPTION NemaPath viewer EC 3.6.1.- NO DESCRIPTION NemaPath viewer
Peptidoglycan biosynthesisEC 2.4.1.129 [poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptid NemaPath viewer
Glycosylphosphatidylinositol(GPI)-anchor biosynthesisEC 2.4.1.- NO DESCRIPTION NemaPath viewer EC 2.7.-.- NO DESCRIPTION NemaPath viewer EC 2.3.-.- NO DESCRIPTION NemaPath viewer EC 3.-.-.- NO DESCRIPTION NemaPath viewer
Glycosphingolipid biosynthesis - lactoseriesEC 2.4.1.- NO DESCRIPTION NemaPath viewer
Glycosphingolipid biosynthesis - neo-lactoseriesEC 2.4.1.- NO DESCRIPTION NemaPath viewer
Glycosphingolipid biosynthesis - globoseriesEC 2.4.1.- NO DESCRIPTION NemaPath viewer
Glycosphingolipid biosynthesis - ganglioseriesEC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 2.4.1.- NO DESCRIPTION NemaPath viewer
Glycan structures - biosynthesis 1EC 2.4.1.41 UDP-N-acetyl-D-galactosamine:polypeptide NemaPath viewer EC 2.4.1.- NO DESCRIPTION NemaPath viewer EC 2.7.-.- NO DESCRIPTION NemaPath viewer EC 2.4.1.145 UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha NemaPath viewer EC 2.4.1.119 dolichyl-diphosphooligosaccharide:protein-L-asparagine NemaPath viewer EC 3.2.1.106 mannosyl-oligosaccharide glucohydrolase NemaPath viewer
Glycan structures - biosynthesis 2EC 2.7.-.- NO DESCRIPTION NemaPath viewer EC 2.4.1.- NO DESCRIPTION NemaPath viewer EC 2.-.-.- NO DESCRIPTION NemaPath viewer
Glycan structures - degradationEC 3.5.1.26 N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase NemaPath viewer |
1.8 Biosynthesis of Polyketides and Nonribosomal Peptides
Biosynthesis of 12-, 14- and 16-membered macrolides
Polyketide sugar unit biosynthesisEC 4.2.1.46 dTDP-glucose 4,6-hydro-lyase NemaPath viewer
Biosynthesis of ansamycins
Type I polyketide structures
Biosynthesis of siderophore group nonribosomal peptidesEC 2.7.7.- NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer
Nonribosomal peptide structures
Biosynthesis of vancomycin group antibioticsEC 4.2.1.46 dTDP-glucose 4,6-hydro-lyase NemaPath viewer
Biosynthesis of type II polyketide backboneEC 4.-.-.- NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer
Biosynthesis of type II polyketide productsEC 1.1.1.- NO DESCRIPTION NemaPath viewer |
1.9 Metabolism of Cofactors and Vitamins
Ubiquinone biosynthesisEC 3.1.2.- NO DESCRIPTION NemaPath viewer EC 1.6.5.3 NADH:ubiquinone oxidoreductase NemaPath viewer EC 4.1.1.- NO DESCRIPTION NemaPath viewer EC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 2.1.1.- NO DESCRIPTION NemaPath viewer
One carbon pool by folate
Thiamine metabolismEC 3.6.1.15 unspecific diphosphate phosphohydrolase NemaPath viewer EC 3.1.3.- NO DESCRIPTION NemaPath viewer
Riboflavin metabolismEC 1.14.18.1 monophenol,L-dopa:oxygen oxidoreductase NemaPath viewer EC 3.5.4.25 GTP 7,8-8,9-dihydrolase (diphosphate-forming) NemaPath viewer EC 3.1.3.- NO DESCRIPTION NemaPath viewer
Vitamin B6 metabolismEC 4.-.-.- NemaPath viewer
Nicotinate and nicotinamide metabolismEC 3.7.1.- NO DESCRIPTION NemaPath viewer EC 2.7.1.- NO DESCRIPTION NemaPath viewer EC 3.1.3.- NO DESCRIPTION NemaPath viewer
Pantothenate and CoA biosynthesisEC 2.2.1.6 pyruvate:pyruvate acetaldehydetransferase (decarboxylating) NemaPath viewer
Biotin metabolismEC 3.4.-.- NO DESCRIPTION NemaPath viewer EC 2.3.1.47 6-carboxyhexanoyl-CoA:L-alanine C-carboxyhexanoyltransferase NemaPath viewer
Lipoic acid metabolism
Folate biosynthesisEC 2.7.6.3 ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine NemaPath viewer EC 3.6.1.- NO DESCRIPTION NemaPath viewer
Retinol metabolismEC 1.1.1.105 retinol:NAD+ oxidoreductase NemaPath viewer
Porphyrin and chlorophyll metabolismEC 6.1.1.17 L-glutamate:tRNAGlu ligase (AMP-forming) NemaPath viewer EC 2.3.1.37 succinyl-CoA:glycine C-succinyltransferase (decarboxylating) NemaPath viewer EC 6.6.1.1 Mg-protoporphyrin IX magnesium-lyase NemaPath viewer EC 4.-.-.- NemaPath viewer EC 4.99.1.3 cobalt-sirohydrochlorin cobalt-lyase (sirohydrochlorin-forming) NemaPath viewer EC 1.-.-.- NO DESCRIPTION NemaPath viewer |
1.10 Biosynthesis of Secondary Metabolites
Puromycin biosynthesis
Caffeine metabolism
Tetracycline biosynthesisEC 6.4.1.2 acetyl-CoA:carbon-dioxide ligase (ADP-forming) NemaPath viewer
Penicillin and cephalosporin biosynthesisEC 3.5.2.6 beta-lactam hydrolase NemaPath viewer
beta-Lactam resistanceEC 3.5.2.6 beta-lactam hydrolase NemaPath viewer
Clavulanic acid biosynthesis
Novobiocin biosynthesis
Benzoxazinone biosynthesis
Streptomycin biosynthesisEC 4.2.1.46 dTDP-glucose 4,6-hydro-lyase NemaPath viewer
Terpenoid biosynthesis
Indole and ipecac alkaloid biosynthesisEC 4.1.1.28 aromatic-L-amino-acid carboxy-lyase NemaPath viewer
Monoterpenoid biosynthesis
Limonene and pinene degradationEC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 1.14.-.- NO DESCRIPTION NemaPath viewer EC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 3.7.1.- NO DESCRIPTION NemaPath viewer EC 3.1.2.- NO DESCRIPTION NemaPath viewer
Diterpenoid biosynthesis
Brassinosteroid biosynthesisEC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 1.14.-.- NO DESCRIPTION NemaPath viewer EC 1.3.99.- NO DESCRIPTION NemaPath viewer
Zeatin biosynthesis
Phenylpropanoid biosynthesisEC 1.14.-.- NO DESCRIPTION NemaPath viewer EC 1.11.1.7 donor:hydrogen-peroxide oxidoreductase NemaPath viewer EC 4.1.1.- NO DESCRIPTION NemaPath viewer EC 5.2.1.- NO DESCRIPTION NemaPath viewer
Flavonoid biosynthesis
Anthocyanin biosynthesisEC 2.1.1.- NO DESCRIPTION NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 2.4.1.- NO DESCRIPTION NemaPath viewer
Isoflavonoid biosynthesisEC 1.14.13.- NO DESCRIPTION NemaPath viewer
Flavone and flavonol biosynthesis
Alkaloid biosynthesis IEC 1.14.18.1 monophenol,L-dopa:oxygen oxidoreductase NemaPath viewer EC 4.1.1.28 aromatic-L-amino-acid carboxy-lyase NemaPath viewer EC 4.1.1.25 L-tyrosine carboxy-lyase (tyramine-forming) NemaPath viewer EC 4.1.1.- NO DESCRIPTION NemaPath viewer
Alkaloid biosynthesis IIEC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 3.1.1.- NO DESCRIPTION NemaPath viewer EC 3.1.1.1 carboxylic-ester hydrolase NemaPath viewer
Insect hormone biosynthesisEC 3.1.1.59 methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-die NemaPath viewer EC 1.-.-.- NO DESCRIPTION NemaPath viewer EC 1.1.1.- NO DESCRIPTION NemaPath viewer EC 2.1.1.- NO DESCRIPTION NemaPath viewer
Acridone alkaloid biosynthesis |
1.11 Xenobiotics Biodegradation and Metabolism
Geraniol degradationEC 1.1.1.35 (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase NemaPath viewer EC 1.3.99.- NO DESCRIPTION NemaPath viewer EC 5.2.1.- NO DESCRIPTION NemaPath viewer EC 2.3.1.16 acyl-CoA:acetyl-CoA C-acyltransferase NemaPath viewer
1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradationEC 4.1.1.- NO DESCRIPTION NemaPath viewer EC 3.7.1.- NO DESCRIPTION NemaPath viewer
gamma-Hexachlorocyclohexane degradationEC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 1.14.-.- NO DESCRIPTION NemaPath viewer EC 3.8.1.5 1-haloalkane halidohydrolase NemaPath viewer
Benzoate degradation via hydroxylationEC 3.1.1.24 4-carboxymethylbut-3-en-4-olide enol-lactonohydrolase NemaPath viewer EC 2.3.1.16 acyl-CoA:acetyl-CoA C-acyltransferase NemaPath viewer EC 3.7.1.- NO DESCRIPTION NemaPath viewer EC 4.1.1.- NO DESCRIPTION NemaPath viewer
Bisphenol A degradationEC 1.1.1.- NO DESCRIPTION NemaPath viewer EC 1.14.13.- NO DESCRIPTION NemaPath viewer
Fluorobenzoate degradation
Biphenyl degradationEC 3.7.1.- NO DESCRIPTION NemaPath viewer EC 4.1.1.- NO DESCRIPTION NemaPath viewer
Toluene and xylene degradationEC 1.14.13.- NO DESCRIPTION NemaPath viewer
2,4-Dichlorobenzoate degradationEC 3.1.1.- NO DESCRIPTION NemaPath viewer
1- and 2-Methylnaphthalene degradationEC 1.3.99.- NO DESCRIPTION NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 4.1.1.- NO DESCRIPTION NemaPath viewer
Tetrachloroethene degradationEC 1.1.1.- NO DESCRIPTION NemaPath viewer EC 3.3.2.10 epoxide hydrolase NemaPath viewer
Naphthalene and anthracene degradationEC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 2.1.1.- NO DESCRIPTION NemaPath viewer EC 3.8.1.5 1-haloalkane halidohydrolase NemaPath viewer EC 1.14.-.- NO DESCRIPTION NemaPath viewer
1,4-Dichlorobenzene degradationEC 1.14.-.- NO DESCRIPTION NemaPath viewer EC 1.14.13.- NO DESCRIPTION NemaPath viewer
Fluorene degradationEC 4.1.1.- NO DESCRIPTION NemaPath viewer
Carbazole degradation
1,2-Dichloroethane degradationEC 3.8.1.5 1-haloalkane halidohydrolase NemaPath viewer EC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer
Benzoate degradation via CoA ligationEC 1.1.1.35 (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase NemaPath viewer EC 3.1.2.- NO DESCRIPTION NemaPath viewer EC 1.14.13.- NO DESCRIPTION NemaPath viewer EC 3.7.1.- NO DESCRIPTION NemaPath viewer EC 1.1.1.- NO DESCRIPTION NemaPath viewer EC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 2.7.1.- NO DESCRIPTION NemaPath viewer EC 1.3.99.- NO DESCRIPTION NemaPath viewer EC 2.3.1.9 acetyl-CoA:acetyl-CoA C-acetyltransferase NemaPath viewer
Trinitrotoluene degradationEC 1.-.-.- NO DESCRIPTION NemaPath viewer
3-Chloroacrylic acid degradationEC 4.1.1.- NO DESCRIPTION NemaPath viewer EC 1.2.1.3 aldehyde:NAD+ oxidoreductase NemaPath viewer EC 3.8.1.5 1-haloalkane halidohydrolase NemaPath viewer
Ethylbenzene degradationEC 2.3.1.- NO DESCRIPTION NemaPath viewer EC 3.7.1.- NO DESCRIPTION NemaPath viewer EC 2.3.1.16 acyl-CoA:acetyl-CoA C-acyltransferase NemaPath viewer
Styrene degradationEC 1.14.13.- NO DESCRIPTION NemaPath viewer
Atrazine degradation
Caprolactam degradationEC 1.1.1.35 (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase NemaPath viewer EC 3.7.1.- NO DESCRIPTION NemaPath viewer EC 3.5.2.- NO DESCRIPTION NemaPath viewer EC 1.3.99.- NO DESCRIPTION NemaPath viewer
Metabolism of xenobiotics by cytochrome P450 |