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KEGG ASSOCIATIONS

A Note on KEGG (Kyoto Encyclopedia of Genes and Genomes):
KEGG is a suite of databases and associated software, integrating our current knowledge on molecular interaction networks in biological processes (PATHWAY database), the information about the universe of genes and proteins (GENES/SSDB/KO databases), and the information about the universe of chemical compounds and reactions (COMPOUND/REACTION databases). For more information see: KEGG: Kyoto Encyclopedia of Genes and Genomes

A Note about how we make KEGG associations:
Enzyme Commision (EC) numbers are assigned to nematode EST contigs by primary sequence similarity. The EC numbers are then lit up in every pathway in which those enzymes are represented. We do not provide exhaustive curation, therefore proper interpretation requires the users' cognizance of the metabolic pathways.


Sequences used for KEGG associations:
To eliminate data redundancy, ESTs are clustered by identity into contigs and further organized into clusters. ESTs within a contig derive from nearly identical transcripts whereas contigs within a cluster may represent splice isoforms of a gene or transcripts from multigene families with extremely high sequence identity (Mitreva et al, 2004). The KEGG associations are done on the contig level. For summarizing the associations on cluster level use the contig-cluster membership files available here.


Instructions relevant to this page:
To view KEGG associations for any of the listed species below, simply click on the KEGGv40 viewer link, then provide a user-defined cutoff. For an expandable tree view of pathway associations for each listed species at a cutoff of 1e-05, click on the TreeView link.


last update: 7-26-07
Genomes
#Genes
NemaPath Treeview
NemaPath KEGGview
Ancylostoma caninum_Annotation_EST
9113
Brugia malayi_Annotation
11749
Caenorhabditis elegans_wormbaseV160
23144
EST contigs
#Contigs
NemaPath Treeview
NemaPath Kegg Data
Ancylostoma caninum
5484
Ancylostoma ceylanicum
4953
Ascaris suum
17949
Brugia malayi
1609
Dirofilaria immitis
2534
Ditylenchus africanus
5214
Globodera pallida
3406
Globodera rostochiensis
6448
Haemonchus contortus
9842
Heterodera glycines
12313
Heterodera schachtii
1600
Meloidogyne arenaria
3372
Meloidogyne chitwoodi
5880
Meloidogyne hapla
11193
Meloidogyne incognita
9107
Meloidogyne javanica
5172
Meloidogyne paranaensis
2263
Nippostrongylus brasiliensis
3949
Onchocerca flexuosa
1665
Ostertagia ostertagi
4831
Parastrongyloides trichosuri
4934
Pratylenchus penetrans
488
Pristionchus pacificus
2654
Radopholus similis
4004
Strongyloides ratti
5237
Strongyloides stercoralis
3479
Toxocara canis
2135
Trichinella spiralis
5958
Trichuris muris
3735
Trichuris vulpis
1690
Xiphinema index
5485
Zeldia punctata
202

 

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 Genome Sequencing Center
 Washington University
 School of Medicine
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