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News & Announcements March 2013
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New Postdoc position available!
The Integrated Genomics group at The Genome Institute is hiring. The successful candidate will be part of an established and successful research group focused on integrating 'omics' approaches aimed at understanding organisms at a molecular level. Please read the job description for more details.
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NemaGene Gene Tables added to Nematode.net
This new feature of Nematode.net hosts annotations made to final genesets. Tables typically provide clustering information, KO, IPR and GO assignments and more. Our first table loaded is for Brugia malayi (more coming soon). Check out the NemaGene Gene Tables for yourself.
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CDS for 10 final genesets now available in NemaBLAST
The NemaBLAST vs. EST contigs & genes blast service now hosts CDS for 10 final genesets with the most recent addition of 18,074 B.xylophilus genes. These CDS are now available for integration into your choice of blast dbs to search. NemaBLAST vs. EST contigs & genes. Fasta for these CDS is also available in our Data Download section.
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Next-gen transcript assembly data available - A resource allowing the user to download recent, 454-based, transcript assembly data. Nucleotide & translated protein fasta files for isotig consensus, isogroup membership and isotig membership files are all available for download, along with statistics about the assembly itself.
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Taylor CM, Martin J, Rao RU, Powell K, Abubucker S, Mitreva M. (2013) Using existing drugs as leads for broad spectrum anthelmintics targeting protein kinases. PLoS Pathog. Feb;9(2):e1003149. doi: 10.1371/journal.ppat.1003149. Epub 2013 Feb 14. link
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Heizer E, Zarlenga DS, Rosa B, Gao X, Gasser RB, De Graef J, Geldhof P, Mitreva M. (2013) Transcriptome analyses reveal protein and domain families that delineate stage-related development in the economically important parasitic nematodes, Ostertagia ostertagi and Cooperia oncophora. BMC Genomics. Feb 22;14(1):118. [Epub ahead of print] link
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Menon R, Gasser RB, Mitreva M, Ranganathan S. (2013) An analysis of the transcriptome of Teladorsagia circumcincta: its biological and biotechnological implications BMC Genomics Suppl 7:S10. doi: 10.1186/1471-2164-13-S7-S10. Epub 2012 Dec 13. link
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DE Graef J, Demeler J, Skuce P, Mitreva M, VON Samson-Himmelstjerna G, Vercruysse J, Claerebout E, Geldhof P. (2013) Gene expression analysis of ABC transporters in a resistant Cooperia oncophora isolate following in vivo and in vitro exposure to macrocyclic lactones. Parasitology Apr;140(4):499-508. doi: 10.1017/S0031182012001849. Epub 2013 Jan 2. link
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Pavan MG, Mesquita RD, Lawrence GG, Lazoski C, Dotson EM, Abubucker S, Mitreva M, Randall-Maher J, Monteiro FA. (2013) A nuclear single-nucleotide polymorphism (SNP) potentially useful for the separation of Rhodnius prolixus from members of the Rhodnius robustus cryptic species complex (Hemiptera: Reduviidae). Infect Genet Evol. Mar;14:426-33. doi: 10.1016/j.meegid.2012.10.018. Epub 2012 Dec 6. link
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McNulty SN, Mitreva M, Weil GJ, Fischer PU. (2013) Inter and intra-specific diversity of parasites that cause lymphatic filariasis. Infect Genet Evol. Mar;14:137-46. doi: 10.1016/j.meegid.2012.11.002. Epub 2012 Nov 29. link
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Wang J, Mitreva M, Berriman M, Thorne A, Magrini V, Koutsovouls G, Kumar S, Blaxter ML, Davis RE. (2012) Silencing of Germline-Expressed Genes by DNA Elimination in Somatic Cells. Developmental Cell 01 November 2012 doi:10.1016/j.devcel.2012.09.020 (link)
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